CVE WatchSep 23, 2026

CVE-2026-54604

OpenSlide is a C library for reading whole slide image files. Prior to 4.0.1, a behavior change in libtiff 4.7.1 causes the indirect TIFF ti

CVSS

—

No CVSS

EPSS

0.5%

p45

KEV

—

Exploit Today

0-100

Published: Sep 17, 2026 · Last modified: Sep 23, 2026 · CWE-758 · CWE-908

EPSS · 30d

0.5%EPSS · 30 days0.5%

2026-10-102026-11-07

Technical description

OpenSlide is a C library for reading whole slide image files. Prior to 4.0.1, a behavior change in libtiff 4.7.1 causes the indirect TIFF tile path in src/openslide-decode-tiff.c and _openslide_tiff_read_tile() to request a full-height destination for a partial bottom tile row, allowing uninitialized heap memory to enter pixel data returned by openslide_read_region(). A crafted but valid slide can trigger the issue in TIFF-based formats other than Hamamatsu NDPI when a network service renders attacker-provided slides. Successful extraction depends on pixel transparency handling and recompression, OpenSlide with libtiff 4.7.0 or earlier is not affected, and official binary builds 4.0.0.10 and 4.0.0.11 are affected. This issue is fixed in OpenSlide 4.0.1 and official binary build 4.0.0.12.

Official references

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